过冷度对窄缝通道内单蒸汽泡运动特性影响的实验研究

对窄缝通道内过冷条件下单蒸汽泡运动特性进行了实验研究，分析了过冷度对单蒸汽泡运动特性的影响。实验结果表明，过冷条件下，单蒸汽泡在上升过程中，其尺寸不断减小，形状也不断改变；单蒸汽泡界面存在冷凝现象，过冷度越大，直径减小越快，同一直径蒸汽泡的纵横比在一个范围内波动；过冷条件下，单蒸汽泡的z向速度和x向速度都随着直径的增大先增加后减小，均在直径约10 mm时具有最大值；单蒸汽泡z向速度则随着过冷度的增大而增大，而x向速度在零上下波动，随过冷度增大略有增大。过冷度会影响窄缝通道内单蒸汽泡的行为特性，并进一步影响流型形成与演变。      

An integrated bioinformatics analysis and experimental study identified key biomarkers CD300A or CXCL1, pathways and immune infiltration in diabetic nephropathy mice

Diabetic nephropathy (DN) is a common microvascular complication that easily leads to end-stage renal disease. It is important to explore the key biomarkers and molecular mechanisms relevant to diabetic nephropathy (DN). We used highthroughput RNA sequencing to obtain the genes related to DN glomerular tissues and healthy glomerular tissues of mice. Then we used LIMMA to analyze differentially expressed genes (DEGs) between DN and non-diabetic glomerular samples. And we performed KEGG, gene ontology functional (GO) enrichment, and gene set enrichment analysis to reveal the signaling pathway of the disease. The CIBERSORT algorithm based on support vector machine was used to determine the immune infiltration score. Random forest algorithm and Cytoscape obtained hub genes. Finally, we applied co-staining, immunohistochemical staining, RT-qPCR and western blotting to validate the protein and mRNA expression of both hub genes. We obtained 913 DEGs mainly related to inflammatory factors and immunity. GSEA results showed that differential genes were mainly enriched in IL-17 signaling pathway, lipid and atherosclerosis, rheumatoid arthritis, TNF signaling pathway, neutrophil extracellular trap formation, Staphylococcus aureus infection and other pathways. The intersection of the random forest algorithm and Cytoscape revealed both hub genes of CD300A and CXCL1. Experiments have shown that the both key genes of CD300A and CXCL1 shown increased expression in glomerular podocytes, and are related to the inflammation of diabetic nephropathy. And immunohistochemical staining and RT-qPCR further confirmed that the protein and mRNA expression level of CD300A or CXCL1 in glomeruli tissue in DN mice were increased. The expression levels of CD300A and CXCL1 increased significantly under HG (high glucose) stimulation, further confirming that diabetes can lead to increased levels of CD300A and CXCL1 at the cellular level. Through bioinformatics analysis, machine learning algorithms, and experimental research, CD300A and CXCL1 are confirmed as both potential biomarkers in diabetic nephropathy. And we further revealed the main pathways of differential genes and the differentially distributed immune infiltrating cells in diabetic nephropathy.     

Characteristics of as-prepared biochar derived from catalytic pyrolysis within moderate-temperature ionic liquid for CO2 uptake

A promising biochar as solid adsorbent for CO₂ uptake was prepared by the catalytic pyrolysis of coconut shell in moderate-temperature ionic liquid (IL). Then, it was characterized by means of SEM, EDS, BPEA, BET, NLDFT, FTIR, and TG-DSC, and a mechanism interpretation of the porous biochar formation was conducted. In addition, the adsorption characteristics of CO₂ on the as-prepared biochar, such as adsorption capacity, adsorption potential, isosteric heat, and static selectivity at different adsorption temperatures and pressures, were systematically evaluated. The results indicated that the as-prepared biochar exhibited an adequate CO₂ adsorption with a capacity of 4.5 mmol/g at 273 K and 100 kPa. Then, a significant number of slit-like pores were revealed to exist on the as-prepared biochar with a peak pore size between a range of 0.6 nm-2 nm. The porous structure formation was ascribed to the release of carbon-, hydrogen-, oxygen-, sulphur-, and nitrogen-containing compounds during biochar preparation. Meanwhile, both the adsorption potential and isosteric heat of the CO₂ uptake under the tested conditions decreased with an increase in the adsorption capacity, which ranged from 33 kJ/mol-21 kJ/mol and 23 kJ/mol-7 kJ/mol, respectively. Therefore, the isosteric heat could be considered as a piecewise function of adsorption capacity. In addition, the molar ratios of CO₂ over N₂ adsorbed under the tested conditions were above 11 and were accompanied by molar ratio peaks of 26 at 273 K and 19 at 298 K, respectively. Moreover, an interesting phenomenon occurred: the static adsorptive selectivity of CO₂ over N₂ first increased and then decreased and there was an increase in the adsorption pressure at the tested adsorption temperatures.     

煤矿用螺杆式移动空气压缩机在陈四楼煤矿的应用和技术改造

通过对煤矿用螺杆式移动空气压缩机结构、性能、工作原理的研究分析、技术改造和设备投入使用前后的经济性比较,指出了该设备在现代化矿井生产应用中的重要性。     

改性方式对膨润土性能及微粒助留助滤效果的影响

采用中性试剂氟化钠对钙基膨润土进行改性制备膨润土悬浮液和膨润土固体粉末,并分别与CPAM组成微粒助留体系。X-衍射分析表明,中性改性剂氟化钠在用量4%时都可以将膨润土中的Ca2 交换完全;透射电镜观察、膨胀倍、胶质价、粒度、粘度、Zeta电位测定和动态滤水实验表明,相对于膨润土固体粉末,膨润土悬浮液颗粒呈完全剥离的片状结构,具有更好的胶体与分散性能,粒度小、悬浮液流动性好且对二次纤维具有更好的助留助滤效果,尤其是放置四周后仍能保持其良好的助留助滤效果。     

不规则岩矿块抗压强度测定方法

使用分形、混沌理论建立理论上较为严谨的确定不规则岩矿块强度的新方法。测定不规则岩矿块体的最大尺寸、最小尺寸、质量等物理参数后进行直接加压试验。由试验数据计算抗压强度。生产实践表明，所得强度数据准确、符合实际情况。而且简单易行。无需加工试件。     

伊宁铀矿某矿床地浸浸出液中平均铀质量浓度的预测

介绍了矿床采区浸出液中平均铀质量浓度的预测原理、方法和实例，并讨论了存在的问题。     

超强吸水树脂与原土混合作为地源热泵回填材料的实验研究

将超强吸水树脂混合于原土中作为回填材料,在制热工况下分别对使用螺旋盘管、U型管地下换热器时地源热泵系统的性能进行了实验研究,得出了系统的性能变化曲线。实验结果表明,超强吸水树脂与原土混合作为回填材料能够增大地下换热器的换热量,提高地源热泵系统的效率和稳定性,适合于在干旱、岩土体非饱和及地下水位较低的地区应用。     

长江陆溪口水道航道整治方案研究

陆溪口水道是长江中游的重点浅水道之一,由于汊道的兴衰交替,航槽也相应变迁,另外由于直港进口、中港汊道中部及出口处碍航浅滩的存在,导致航道维护困难。根据河床演变特点,确定稳定洲滩、增加直港进口分流、改善直港航行条件的工程措施。近十年河势相对稳定,但中港仍在持续弯曲发展,应抓住有利时机对该水道加以整治。